Aim: This study compared the capability of Biopuer MTAD, QMixTM2in1, 17% EDTA, 6.25% Morinda Citrifolia juice, 2% Nano-Chitosan, 2% Chitosan, 2% Chlorhexidine and distilled water in smear layer removal.
Methods: eighty extracted premolars having single root canals were distributed into eight groups allocated to the final irrigant used. Roots were separated in bacco-lingual direction into two equal halves then analyzed using Scanning Electron Microscope (SEM) at the coronal, middle, and apical parts.
Results: In the coronal and middle parts of the roots the Biopure MTAD showed the highest mean values of smear layer elimination, followed by 17% EDTA, QMixTM2in1, and then 6.25% MCJ. While 2% nano-chitosan, 2% chitosan, 2% CHX and distilled water showed the least mean values of smear layer elimination. The capability of smear layer elimination decreased in the apical third for Biopuer MTAD, 17% EDTA, QMixTM2in1and 6.25 % MCJ. It was only inhibited with 2% nano-chitosan, 2%chitosan, 2% CHX and distilled water.
Conclusion: the study concluded that Biopuer MTAD had the highest mean value for smear layer removal in middle, coronal and to a lesser degree in apical thirds.