Objectives: Candida-associated denture stomatitis is the most prevalent form of oral candidiasis affecting 65% of denture wearers. Continuous use of denture adhesives may affect the surface roughness of the denture material and may contribute to Candida adhesion. This study aimed to investigate surface roughness of two chemically different denture materials after exposure to denture adhesives and its relation to in vitro adhesion of Candida albicans.
Materials and Methods: Five groups of both PMMA and UDMA specimens (10 mm 10 mm 2 mm) were prepared (10 specimens in each group). Specimens were immersed in Corega Cream (group 1), Corega Powder (group 2), Olivafix cream (group 3), Protefix cream (group 4) and distilled water (group 5). Specimens were tested for surface roughness, and in vitro Candida albicans adhesion.
Results: The results showed that Corega cream had statistically significant effect on surface roughness of both types of resins (P < 0.05). On the other hand the other three types of denture adhesive and distilled water had no statistically significant effect on surface roughness
(P > 0.05).The differences in the Candida count between the UDMA specimens were not statistically significant. On the other hand the Candida count of Corega cream exposed group was statistically significant if compared with other groups in the PMMA resin specimens. The differences in the Candida count between the specimens of both resin groups were statistically non-significant
(P > 0.05)
Conclusions: Exposure to Corega cream denture adhesives may induce changes in surface roughness of denture base materials. Candida albicans adhesion is not necessarily increased on denture base materials that are exposed to denture adhesives.