This study aimed to evaluate the fracture resistance of teeth obturated with different adhesive obturation systems. Seventy freshly human extracted single rooted teeth were selected. The samples were biomechanically prepared and classified according to the type of the obturating material into four groups as follows; Group 1; (21 samples) obturated with conventional gutta-percha and AD-seal sealer (META, Chungcheongbuk-do, Korea). Group 2; (21 samples) obturated with ActivGP cones and Activ GP sealer (Brasseler, Savannah, USA). Group 3; (21 samples) obturated with resilon cones and Epipheny sealer (Pentron,Wallingford,USA). Group 4; Control group (unobturated). The samples were further classified according to the observation time into: Subgroup A; (7 samples) after one week. Subgroup B; (7 samples) after one month and Subgroup C; (7 samples) after three month. Samples were loaded vertically after obturation using Universal Testing Machine until fracture. It was found that ActivGP showed the highest resistance followed by Resilon then conventional gutta-percha. It was concluded that Activ Gpobturating system can strengthen the endodontically treated teeth more than Resilon/Epipheny system.