The primary goal of alveolar ridge preservation procedures is volume preservation, the volume preserved by encouraging new bone formation in healing sockets. About 90% of patients referred for implant therapy must perform these procedures after extraction that employs the placement of grafting materials.
Objective: Evaluate and characterize the healing responses of Growth hormone, and bicalcium phosphate mixture in tooth extraction sockets of a canine model.
Materials and Methods: Six mongrel dogs were included in this study; they were divided into 2 groups according to the time of sacrifice (4 and 8 weeks). Each of these groups includes three animals. Animals were subjected to extraction of the third premolar bilaterally, The right side was treated with a mixture of 4 IU (1.6mg) Growth hormone and easy-graft TM (a composite of hydroxyapatite and bèta-tricalcium phosphate – crystal ) 1 x 0.15 ml (450-650 µm) in a granular form before wound closure while the left side was left as a control. The healing extraction sockets were evaluated by Fourier Transform Infrared spectroscopic analysis.
Results: All sockets healed without complications. Growth hormone and biphasic calcium phosphate groups showed new bone formation comparable to that of native bone.
Conclusion: The grafted sockets demonstrated acceptable biodegradability at 4 and 8 weeks postoperatively. The new bone formation was not delayed because of the graft.