Introduction: Regenerative endodontics is a promising alternative treatment for immature teeth with necrotic pulps.
Aim of the study: The present study was performed to assess healing potential of young permanent immature teeth with necrotic pulp after the following treatment protocols: (1) Calcium hydroxide apexification, (2) the regenerative endodontic protocol (blood clot scaffold).
Materials and Methods: Immature necrotic permanent maxillary central incisors (n = 48) were divided into 2 groups according to the treatment protocol: the apexification group (calcium hydroxide), the REG group (regenerative endodontic protocol). Follow-up was done up to 18 months. Standardized radiographs were digitally evaluated for an increase in root length and thickness, a decrease in the apical diameter Follow-up was done up to 18 months.
Results: After a follow-up period of 18 months, most of the cases showed radiographic evidence of periapical healing. Groups showed a progressive increase in root length and width and a decrease in apical diameter.
Conclusions: The regenerative endodontic procedure allowed the continued development of roots in teeth with necrotic pulps.