Aim: This randomized clinical study evaluated and compared the three years clinical performance of self-adhering flowable composite with or without EDTA surface treatment in Class V restorations. Materials and Methods: Thirty patients, each with three moderate cervical carious lesions, were enrolled in the present single – center study. Total 90 restorations were randomly assigned by one operator not involved in the restoration or the evaluation procedures, in each patient, one lesion was allocated to be restored using self-adhering flowable composite (Fusio liquid Dentin (FL)) without surface treatment, the second using self-adhering flowable composite (Fusio liquid Dentin after EDTA(EFL))  surface treatment, the third to be restored using conventional flowable composite (Tetric Flow (FF)). The allocation sequence of restorations was concealed from the operator in sealed and stapled envelopes. A single operator restored all the preparations according to the manufacturer's instructions. The restorations were finished and polished immediately after placement. Clinical evaluation was performed at one week, six, 12,18,24,30, and 36 months, by independent examiner according to United States Public Health Services (USPHS), modified Ryge criteria. Statistical analysis was performed by IBM SPSS Statistics for Windows, Version 22.0. Armonk, NY: IBM Corp. Results: Two cases could not be reassessed at 18 and 30 months follow up. Time significantly affects the clinical performance within the tested groups except the  marginal integrity criterion with the EFL group. However there was significant different between the three groups at 36 months interval in marginal discoloration, marginal integrity criteria.  No significant differences were observed between the tested materials from baseline to those of three years in the other USPHScriteria. Conclusions: Self-adhering light cured resin composite achieved clinical acceptable performance at three years follow up interval. The combination of EDTA/ self-adhering light cured resin composite reveals enhancement of the clinical stability and durability of the restorations over time.