Objective: The aim of the study was to compare and evaluate Hyflex CM files and M-Pro files versus Protaper Next files regarding the amount of apically extruded debris in the mesial root canals of mandibular molars.
Methodology: Sixty three human permanent mandibular molars were utilized in the study. Empty Eppendorf tubes were weighed using an analytical balance three times and an average weight was calculated (W1). Then, a hole was created in the stopper of the Eppendorf tubes and mesial roots were inserted. The roots were randomly assigned into 3 groups according to the instrumentation technique used: Group I: Protaper Next (n=21), Group II: Hyflex (n=21) and Group III: M-Pro (n=21). Distilled water was used as an irrigant in all groups. After instrumentation, the vials were placed in an incubator for 3 days and the apically extruded debris collected in the Eppendorf tubes were weighed again (W2) after instrumentation. Welch test was used for comparison between the three groups.
Results: There was no statistically significant difference between the amount of debris extrusion of the three groups (P=0.204).
Conclusion: Within the limitation of this study it was concluded that all systems were associated with extrusion of debris.