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72555

The Effectiveness of Vitamin D Supplementation in Chronic Periodontitis Patients: a Randomized Controlled Clinical Trial

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Last updated: 23 Dec 2024

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Abstract

Background : Vitamin D deficiency is a common health problem worldwide and linked to some infectious and inflammatory conditions, including periodontal disease. This is a double blind randomized controlled study to evaluate the clinical effectiveness of Vitamin D supplementation as an adjunct therapy to non-surgical periodontal treatment in healthy middle-aged vitamin D deficient patients with chronic periodontitis.
Material and Methods: Twenty eight patients with mild to moderate chronic periodontitis were included in this study . They were randomized to two groups: Test Group taking oral Vitamin D supplementation 10,000 IU one tablet daily for five days per week for a total duration of 12 weeks and Control Group taking placebo pills. Both groups were maintained on scaling and root planning sessions. Data was collected at baseline and at three months including the following clinical periodontal parameters: Gingival index (GI), Plaque index (PI), Probing pocket depth (PPD) and Clinical attachment level (CAL).
Results: Intra-group analysis showed that both groups had significant improvements in the periodontal measures. However, analysis comparing changes in the mean periodontal indices between groups showed that the mean changes across all periodontal indices between groups were statistically significant at pConclusion: Adjunctive low cost Vitamin D supplementation in mild to moderate chronic periodontitis in middle aged Vitamin D deficient healthy patients significantly improves clinical periodontal outcomes relative to scaling and root planning alone with no side effects. Vitamin D is safe and probably may contribute to decrease health care costs as an adjunctive therapy to conventional periodontal treatment.

DOI

10.21608/edj.2019.72555

Keywords

Chronic Periodontitis, vitamin D deficiency, periodontal diseases/drug therapy, calcitriol/therapeutic use

Authors

First Name

Assaf

Last Name

M

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Affiliation

Oral Surgical Sciences Department, Division of Periodontology, Faculty of Dentistry, Beirut Arab University, Lebanon

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Orcid

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First Name

Nayer

Last Name

Aboelsaad

MiddleName

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Affiliation

Associate Professor, Periodontology, Faculty of Dentistry, Beirut Arab University, Lebanon; and Faculty of Dentistry, Mansoura University, Egypt.

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Volume

65

Article Issue

Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)

Related Issue

10692

Issue Date

2019-04-01

Receive Date

2020-02-21

Publish Date

2019-04-01

Page Start

1,311

Page End

1,321

Print ISSN

0070-9484

Online ISSN

2090-2360

Link

https://edj.journals.ekb.eg/article_72555.html

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https://edj.journals.ekb.eg/service?article_code=72555

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16

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Original Article

Type Code

254

Publication Type

Journal

Publication Title

Egyptian Dental Journal

Publication Link

https://edj.journals.ekb.eg/

MainTitle

The Effectiveness of Vitamin D Supplementation in Chronic Periodontitis Patients: a Randomized Controlled Clinical Trial

Details

Type

Article

Created At

22 Jan 2023