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227279

Growth and Developmental Milestones in children with Congenital Hypothyroidism Attending Assiut Health Insurance Clinic.

Article

Last updated: 22 Jan 2023

Subjects

-

Tags

Community Medicine

Abstract

Objective: Determine the effect of CH on growth and ‎ development of children aged 1–60 months compared to normal children.
Methodology: A cross sectional study with comparison group comprising 118 children with ‎CH and 236 normal children was conducted ‎in Assiut, Egypt. Growth was measured by weight and length/height.‎ Developmental delay was screened using the ASQ3.‎
Results: Mean age in both groups was 19.6 months. Mean weight of CH cases was 6991.3±1907.4 gm versus 6912.3±188.2 gm for normal children in children aged 1- Regarding thyroid function, 15% and 23% of CH cases revealed overt and subclinical hypothyroidism respectively. Overt hypothyroidism showed significantly higher developmental delays than either eu-thyroid or subclinical cases in the communication gross motor, fine motor, and personal–social domains (64.7%, 42.9%, 43.8% and 42,9% respectively)
Conclusion:
CH children were significantly overweight, stunted and developmentally delayed compared to normal children. Impaired thyroid function was not associated with growth defects but overt hypothyroid cases showed significant developmental delay.
IQ testing and continuous monitoring are essential for all children with CH. Efficiently organized recording systems, treatment documents, and compliance and follow-up assessment results can facilitate hassle-free health-card retrieval
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DOI

10.21608/ejcm.2022.113872.1199

Keywords

congenital hypothyroidism, developmental milestones, Egypt, Growth, neonatal screening

Authors

First Name

Marian

Last Name

Habib

MiddleName

Maged

Affiliation

Assiut genetic counselling centre, General Administration for Disability Reduction, MOHP, Assiut Governorate, Egypt.

Email

marian.habib@med.aun.edu.eg

City

Assiut

Orcid

-

First Name

Hala

Last Name

Abou faddan

MiddleName

Hassan I

Affiliation

Public health and community medicine, faculty of medicine, Assiut University

Email

halaaboufaddan@yahoo.com

City

Assiut

Orcid

-

First Name

Kotb

Last Name

Metwalley

MiddleName

Abbass

Affiliation

Pediatric endocrinology unit.Pediatric department, Faculty of medicine, Assiut University, Assiut, Egypt

Email

kotb72@aun.edu.eg

City

Assiut

Orcid

-

First Name

Taghreed

Last Name

Ismail

MiddleName

Abdul-Aziz Mohammad

Affiliation

Public Health and Community Medicine Department, Faculty of Medicine, Assiut University

Email

taghrid1973@yahoo.com

City

Assiut

Orcid

-

Volume

40

Article Issue

4

Related Issue

37243

Issue Date

2022-10-01

Receive Date

2021-12-30

Publish Date

2022-10-01

Page Start

233

Page End

242

Print ISSN

1110-1865

Online ISSN

2090-2611

Link

https://ejcm.journals.ekb.eg/article_227279.html

Detail API

https://ejcm.journals.ekb.eg/service?article_code=227279

Order

2

Type

Original Article

Type Code

234

Publication Type

Journal

Publication Title

The Egyptian Journal of Community Medicine

Publication Link

https://ejcm.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023