Objectives: to assess sleep quality among patients with Irritable bowel syndrome (IBS) and to
determine its association with disease severity. Method: a cross-sectional study was applied
on 275 patients with IBS attending Internal Medicine outpatient clinic, Zagazig University
hospital. Diagnosis was established using ROME IV criteria. Patients underwent history
taking and clinical examination. The Sleep quality was measured using the Pittsburgh Sleep < br />Quality Index (PSQI). Fatigue severity scale (FSS) and IBS severity and IBS- severity scoring
system (IBS-SSS) were utilized to measure fatigue and disease severity among patients
respectively. Results: Mean age of patients was 32.43 years. Male represents 59.6% and
47.3% had middle socioeconomic class (SES). About one third had IBS-diarrhea
predominant, and 46.9% had mild form. FSS score fluctuated between 9 to 63 with mean
37.29. Poor sleep quality was present in 52.7%. There was significant relation between sleep < br />quality and marital status, FSS score and IBS severity. There was significant positive
correlation between PSQI global score and both FSS and IBS-SSS. Being married, having
mild, moderate IBS, and low SES significantly increased risk of poor sleep quality by 12.97,
4.71, 2.79, 26.25, folds respectively while lower FSS was a significant protective factor.
Conclusion: Poor sleep quality was prevalent among patient with IBS. Being married, mild,
moderate IBS, and low SES were significant risk factors. Patients should be screened for poor
sleep quality with rapid method as PSQI and patients with abnormal scores should do further
investigations.