The toxicity and teratogenicity of three commonly used drugs were fested in Avil ( 1 - pheny ? - pyridyl - B - dimethyl aminopropane) is an anti. histaminic and antiallergic drug, Nesdonal (a derivative of the acid 2 - ethyl - 5 methyl - 1 -butyl - 5 thiobarbitone) is a general anaesthetic drug, while Revrin ( pyrrolidino. methyl tetracycline) is a common antibiotic.
Antihistaminie drugs are generally thought to be safe, Meclozine for instance has been thouroughly investigated and several independent studies in difierent parts of the world failed to demonstrate any deleterious efiect on the embryo or fcetus (Wollam, f966).