Normal development and function of male reproductive organs are primarily controlled by androgens (N;u et al., 2003). However, estrogen plays also a role in normal development although it is not well defined but this refers to that estrogen receptors (ER) are also present throughout the male reproductive tract. Some studies have documented the effects of exogenous estrogen on reproductive organs of both developing (McLachlan, 1981) and mature (Junlewicz, et aI., 1989) males. Administration of estrogen to developing fetuses or neonates produces pronounced short - and long - term effects on the growth, histology, and functional activity of reproductive organs (William et aI., 1999).