Biological aspects between cultivated and wild sea bass, Dicentrarchus labrax were evaluated. Fish samples were collected seasonally from Boughaz El-Maadiya in the eastern Mediterranean coast and fish farm. The length-weight relationship of seabass from two habitats were calculated and condition factor for seabass captured from El-Maadiya region (Mean ± S.d = 1.044 ± 0.0905) was lower than that for fish farm (Mean ± S.d = 1.158 ± 0.8119). The mean value of natural mortality coefficient for wild seabass was 0.172 ± 0.017. Significant seasonal difference in degrees of stomach fullness of seabass from El-Maadiya region (F = 3.589, df = 3, p<0.05) and fish farm (F = 8.381, df = 3, p<0.01). sex ratio for seabass from El-Maadiya region (X2 =5.21, p < 0.05) differ significantly from cultivated in fish farm. The average of gonadosomatic index (GSI) (0.258 ± 0.2865), hepatosomatic Index (HSI) (1.20 ± 0.5714) and spleen-somatic index (SSI) (0.102 ± 0.0518) for fishes from El-Maadiya region was lower than GSI (0.940 ± 1.5601), HSI (1.486 ± 0.5247) and SSI (0.157 ± 0.2406) for cultured seabass.