Beta
ManageSearchChatDiscover
266680

Skip Metastasis in Papillary Thyroid Cancer: Is it Predictable?

Article

Last updated: 22 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Background: Cervical lymph node metastasis is a prognostic factor in papillary thyroid carcinoma (PTC). Metastasizing PTC to cervical lymph nodes is very common and occurs in 30-80% of patients. 
Aim: To investigate the risk factors of skip lateral lymph node metastasis in PTC patients.
Methods: This retrospective study was conducted at a single institution and included PTC patients treated in the period between 2018 and 2021. All patients with PTC who underwent total thyroidectomy with central and lateral block neck dissection were reviewed for skip metastases which was confirmed by histopathologic examination.
Results: During the study period, 267 patients with PTC underwent total thyroidectomy with central and/or lateral block neck dissection. Among them, only 64 patients matched the study inclusion criteria and their pathology was reviewed for skip metastases. Thirteen (20.3%) patients showed skip metastases. Their mean (±SD) age was 50.1 (±16.7) years and 8 (61.5%) were females. Only age ≥40 years and tumor size ≤0.5 cm differed significantly between patients with skip metastasis and those without.
Conclusions: The results support the conduction of a prospective multi-centric study with a larger sample size to better understand the risk factors for developing skip metastasis in PTC. This would help in selecting patients with a risk for skip metastasis.

DOI

10.21608/resoncol.2022.136368.1167

Keywords

Cervical lymph nodes, Papillary thyroid carcinoma, risk factors, Skip metastasis

Authors

First Name

Mohamed

Last Name

Hafez

MiddleName

T.

Affiliation

Surgical Oncology Department, Mansoura University Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

mthafez@yahoo.com

City

Mansoura

Orcid

0000-0002-7193-9539

First Name

Ahmed

Last Name

Zaki

MiddleName

-

Affiliation

Surgery Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

dr_a_zaki@mans.edu.eg

City

Mansoura

Orcid

-

First Name

Osama

Last Name

Bahy

MiddleName

-

Affiliation

Surgical Oncology Department, Mansoura University Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

osamabahy@mans.edu.eg

City

mansouras

Orcid

-

First Name

Amir

Last Name

Zaid

MiddleName

M.

Affiliation

Surgical Oncology Department, Mansoura University Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

ameirmsdzaid@gmail.com

City

Mansoura

Orcid

-

First Name

Mohamed

Last Name

ElAreeny

MiddleName

-

Affiliation

Mansoura University Hospitals

Email

mohamedw.elareeny@gmail.com

City

Mansoura

Orcid

-

First Name

Merit

Last Name

ElMaadawy

MiddleName

-

Affiliation

Radiology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

dr.merit@yahoo.com

City

Mansoura

Orcid

-

First Name

Shadi

Last Name

Awny

MiddleName

-

Affiliation

Surgical Oncology Department, Mansoura University Oncology Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt

Email

shadiawny@mans.edu.eg

City

mansoura

Orcid

-

Volume

18

Article Issue

2

Related Issue

37904

Issue Date

2022-12-01

Receive Date

2022-04-28

Publish Date

2022-12-01

Page Start

52

Page End

60

Print ISSN

2357-0687

Online ISSN

2357-0695

Article File

RESONCOL_Volume 18_Issue 2_Pages 52-60.pdf

PDF . 333.9kB

Link

https://resoncol.journals.ekb.eg/article_266680.html

Detail API

https://resoncol.journals.ekb.eg/service?article_code=266680

Order

2

Type

Original Article

Type Code

200

Publication Type

Journal

Publication Title

Research in Oncology

Publication Link

https://resoncol.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023