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2577

Effect of Body Mass Index on Survival in Patients with Epithelial Ovarian Cancer

Article

Last updated: 22 Jan 2023

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Abstract

Introduction: Higher body mass index (BMI) is an independent and well-established prognostic factor in hormonerelated
cancers, such as breast and endometrial cancer. As a hormone-dependent cancer, ovarian cancer, however, has been linked inconsistently to obesity. Aim: This work aimed to assess the association between BMI and ovarian cancer survival.
Methods: This retrospective study included 66 patients who were treated for epithelial ovarian cancer from January 2011
to April 2014. Clinical and epidemiological characteristics of patients were collected. Time to progression and overall survival were calculated. BMI was calculated using the formula weight in kilograms divided by the square of the height in meters, and categorized according to World Health Organization classification.Results: BMI indicated underweight in 3 patients (4.5%), healthy weight range in11 (16.7%), pre-obesity in 17 (25.8%),obesity class I in 13 (19.7%), obesity class II in 8 (12.1%) and obesity class III in 14 (21.2%). BMI did not associate significantly with disease stage (p=0.54), pathology (p=0.82), initial CA-125 level (p=0.61), platinum sensitivity(p=0.27), time to progression (p=0.58) or overall survival (p=0.87).Conclusion: Our results suggest prevalence of obesity (relatively high) among Egyptian patients with epithelial ovarian cancer. Noteworthy, BMI had no significant association with disease stage, platinum sensitivity, time-to-progression or overall survival in the studied group.

DOI

10.21608/resoncol.2017.223.1007

Keywords

Ovarian carcinoma, Body Mass Index, Survival

Authors

First Name

Suzy

Last Name

Gohar

MiddleName

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Affiliation

Department of Clinical Oncology, Faculty of Medicine, Menoufia University, Shibin Elkom, Egypt

Email

suzygohar@ymail.com

City

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Orcid

0000-0003-3250-5954

First Name

Ashraf

Last Name

Abdel-Ghany

MiddleName

-

Affiliation

Department of Clinical Oncology, Faculty of Medicine, Menoufia University, Shibin Elkom, Egypt

Email

-

City

-

Orcid

-

First Name

Shaimaa

Last Name

Soliman

MiddleName

-

Affiliation

Department of Public Health and Community Medicine, Faculty of Medicine, Menoufia University, Shibin Elkom, Egypt

Email

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City

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Orcid

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Volume

12

Article Issue

2

Related Issue

345

Issue Date

2016-12-01

Receive Date

2017-04-27

Publish Date

2016-12-01

Page Start

54

Page End

59

Print ISSN

2357-0687

Online ISSN

2357-0695

Link

https://resoncol.journals.ekb.eg/article_2577.html

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https://resoncol.journals.ekb.eg/service?article_code=2577

Order

5

Type

Original Article

Type Code

200

Publication Type

Journal

Publication Title

Research in Oncology

Publication Link

https://resoncol.journals.ekb.eg/

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Article

Created At

22 Jan 2023