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Dosimetric Comparison of 3D Conformal Conventional Radiotherapy versus Intensity-Modulated Radiation Therapy both in Conventional and High Dose Radiation for Prostate Carcinoma

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Last updated: 22 Jan 2023

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Abstract

Background: Radiotherapy plays an important role in the management of prostate cancer. There are ongoing efforts to deliver the optimum radiation dose to the prostate while minimizing it to at risk pelvic structures. Aim: To compare the dose coverage of planning target volume (PTV) and organs-at-risk (OAR) between intensity-modulated radiation therapy (IMRT) and conventional three dimensional conformal radiotherapy (3D-CRT) for the same plan of prostate cancer patients in both conventional dose and high dose. Methods: Plans of 15 prostate cancer patients with low- or intermediate risk, treated by 3D-CRT, were compared with IMRT to the same dose and to a higher dose. We used XIO- treatment planning system for 3D-CRT and Monaco treatment planning system for IMRT. Results: Mean and minimum dose to PTV were equal, but the mean maximum dose was significantly higher in IMRT (72Gy) than 3D-CRT. Doses to critical organs in IMRT plans were lower than 3D-CRT, even in the increased dose of 80Gy. Conclusion: IMRT is recommended as the standard of care in treatment of prostate carcinoma. Applying escalated dose is recommended.

DOI

10.21608/resoncol.2016.588

Keywords

Prostate Cancer, Intensity-modulated radiation therapy, Escalated dose

Authors

First Name

Azza

Last Name

Nasr

MiddleName

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Affiliation

The Department of Radiation Oncology, National Cancer Institute, Cairo University, Cairo, Egypt

Email

nasrazza2@hotmail.com

City

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Orcid

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First Name

Rasha

Last Name

Elawady

MiddleName

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Affiliation

Department of Radiotherapy & Nuclear Medicine, National Cancer Institute, Cairo University, Cairo, Egypt

Email

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City

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Orcid

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Volume

12

Article Issue

1

Related Issue

159

Issue Date

2016-06-01

Receive Date

2016-10-07

Publish Date

2016-06-01

Page Start

10

Page End

14

Print ISSN

2357-0687

Online ISSN

2357-0695

Article File

RESONCOL_Volume 12_Issue 1_Pages 10-14.pdf

PDF . 734.8kB

Link

https://resoncol.journals.ekb.eg/article_588.html

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https://resoncol.journals.ekb.eg/service?article_code=588

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Original Article

Type Code

200

Publication Type

Journal

Publication Title

Research in Oncology

Publication Link

https://resoncol.journals.ekb.eg/

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Article

Created At

22 Jan 2023