This article analyzes the parasitological situation of Cryptosporidiosis in sheep in Azerbaijan now. Fecal isolates of the studied animals were collected in private farms of the Absheron and Shamakhi districts. Fecal isolates were examined at the Laboratory of Biochemistry of Host Parasite Relations of the Institute of Zoology of the National Academy of Sciences of Azerbaijan. Total 120 sheep were examined for cryptosporidium infection. Experiments were carried out in January 2021 to November 2021. Cryptosporidium oocysts detected thin fecal smears were fixed with methyl blue and stained with Carbol-Fuchsin according to Ziehl-Neelsen. Based on research among 120 clinically suspected sheep were examined only 29 (24.2%) had infection – Cryptosporidium sp. In the present study, prevalence of Cryptosporidium infection in relation to season dynamics were also studies. Revealed that prevalence of Cryptosporidium sp. in sheep in Absheron and Shamakhi districts is much higher in autumn (45.7%), spring (20%), and in winter – 16.6 % than summer season (8%).