The effect of sodium butyrate and rosemary leaf meal inclusion on immunoglobulin and oxidative status in breast meat of Arbor Acre broiler birds was investigated. The day-old chicks (n=320) were randomly allotted to 10 dietary treatments that had four replications of 8 birds each. The dietary treatments were allocated as follows : T1= basal diet (BD), T2 = basal diet + 1g/kg Oxytetracycline , T3= BD +2g/kg Sodium butyrate (SB), T4= basal diet +4g SB/kg, T5 = basal diet + 2.5g/kg rosemary leaf meal (RLM), T6=  BD +5.0g/kg RLM , T7= BD +2g/kg SB + 2.5g/kg RLM, T8= BD + 2g/kg SB +5.0g/kg RLM, T9= BD + 4g/kg SB + 2.5g/kg RLM and T10= BD + 4g/kg SB + 5.0g/kg RLM. Results showed that birds fed T1 recorded the lowest (p < 0.05) IgM and IgA values at both phases. The concentration of IgM and IgA for birds fed T4 and T6 were higher (p < 0.05) compared with those in other groups. Birds fed T4 and T6 recorded the highest (p < 0.05) values for superoxide dismutase (SOD) and catalase at both phases when compared with the control groups. At the starter phase, the values for glutathione peroxidase (GPx) was lowest (p < 0.05) in the meat of birds in all the supplemental groups when compared with those of birds in the control groups. It was concluded that; 4 g/kg SB and 5 g/kg RLM supplementation improved the immunoglobulin markers and oxidative status of breast meat in broiler birds.