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71056

Effect of Metamizole (Dipyrone) on Blood and Histological Pictures of Liver and Spleen in Rats

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Last updated: 22 Jan 2023

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Abstract

We used in our study Twenty rats ,divided into two  groups .the first group consist of  10 rats considered as a control group, while the second group treated with 0.05 ml\body weight\day of dipyron injected for 30 days duration. The  toxic effect of dipyrone was obvious in the different tissue and haematotoxic effects  . The histological changes were obvious in the hepatic cell whichof liver were  characterized by atrophy ,irregular hepatic cells ,RBC cells in the blood sinusoid. However,the spleen tissue contains nodule (white pulpe ).The bony tissue have osteocytes large bony vacuoles and the blood vessel were congested.

DOI

10.21608/ejvs.2020.19551.1126

Keywords

Metamizole, Dipyrone, Rats

Authors

First Name

B.

Last Name

Kh. Hameed

MiddleName

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Affiliation

Department of Anatomy and Histology, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.

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Orcid

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First Name

R.

Last Name

M. Fadhil

MiddleName

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Affiliation

Department of Physiology, Pharmacology and Biochemistry, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.

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City

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Orcid

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First Name

Rasha

Last Name

Sh. Hussain

MiddleName

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Affiliation

Department of Biology, Faculty of Education for Pure Science, Tikrit University, Tikrit, Iraq.

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Orcid

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First Name

Buthina

Last Name

A. Abdullah

MiddleName

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Affiliation

Department of Physiology, Pharmacology and Biochemistry, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.

Email

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City

-

Orcid

-

First Name

Kh.

Last Name

A. Hadi

MiddleName

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Affiliation

Department of Physiology, Pharmacology and Biochemistry, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.

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City

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Orcid

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First Name

Wassan

Last Name

S. Obid

MiddleName

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Affiliation

Department of Physiology, Pharmacology and Biochemistry, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.

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City

-

Orcid

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First Name

D.

Last Name

H. Hadree

MiddleName

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Affiliation

Department of Physiology, Pharmacology and Biochemistry, Veterinary Medicine faculty, Tikrit University, Tikrit, Iraq.

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City

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Orcid

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First Name

Enaam

Last Name

A. Gabori

MiddleName

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Affiliation

Department of Medical Laboratory Technique, Al-noor University College, Mosul, Iraq.

Email

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City

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Orcid

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First Name

Nadya

Last Name

E. Mustafa

MiddleName

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Affiliation

General Directorate for Education of Kirkuk, Ministry of education, Iraq.

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Volume

50

Article Issue

The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019

Related Issue

9201

Issue Date

2019-12-01

Receive Date

2019-11-21

Publish Date

2019-12-01

Page Start

89

Page End

94

Print ISSN

1110-0222

Online ISSN

2357-089X

Article File

EJVS_Volume 50_Issue The 8th lnternational Conference of Veterinary Research Division (NRC) Cairo, Egypt , 3rd-5th December, 2019_Pages 89-94.pdf

PDF . 2.3MB

Link

https://ejvs.journals.ekb.eg/article_71056.html

Detail API

https://ejvs.journals.ekb.eg/service?article_code=71056

Order

11

Type

Original Article

Type Code

140

Publication Type

Journal

Publication Title

Egyptian Journal of Veterinary Sciences

Publication Link

https://ejvs.journals.ekb.eg/

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Article

Created At

22 Jan 2023