Recently, the importance of the beneficial elements for humans, animals, and plants has been clarified. Element fortification in plants is an excellent strategy for suppling elements through the food chain. The beneficial elements could promote growth in plants which comprise selenium, silicon, cobalt, and sodium. Nowadays, evaluating the impact of beneficial elements such as selenium and silicon on the growth and productivity of various plant species has become a novel approach. Therefore, field experiment was conducted to evaluate the effect of foliar application of selenium in form of sodium selenite at levels of 10, 20 and 30 μmol, and silicon in form of sodium silicate at levels of 0.5, 1 and 2 mM plus water served as control treatment on vegetative growth, SPAD reading, mineral contents in leaves and seeds, and seed yield and quality of common bean (Phaseolus vulgaris L.)  plants cv. Nebraska during 2020 and 2021 seasons at the Experimental Farm of Horticulture Department, Faculty of Agriculture, Ain Shams University, Qalubia Governorate, Egypt. Results showed that all foliar treatments of selenium and silicon significantly enhanced all vegetative growth parameters, yield and yield quality attributes such as pods yield weight/plant and 100 seed weight, mineral contents in leaves, i.e., N, P, K and Ca as well as Se and Si in seeds as compared with control treatment. In conclusion, foliar spraying of common bean plants cv. Nebraska with Si at 2 mM or Se at 20 μmol enhanced growth, minerals content, yield and yield quality of the plants and subsequently improve the elements fortification at the food chain to humans.