NEUTRON activation of tin metal and cobalt chloride targets for production of ¹¹³Sn and ¹²⁵Sb and ⁶⁰Co was carried out in Egypt's Second Research Reactor (ETRR-2). The ¹¹³Sn, ¹²⁵Sb and 60Co were loaded onto zirconium silicotungestate gel matrix from aqueous solution at pH 1 by the batch technique. The results obtained during the adsorption process of radionuclides were explained through the Visual MINTEQ program version 3. Then 1 and 0.1g of ¹¹³Sn. 125Sb and 60Co-ZrSiW were packed into the volume and planar sealed sources, made of Chinese Artelon, respectively. The radioactivity levels of ¹¹³Sn, ¹²⁵Sb and ⁶⁰Co were measured and found to be (2.96±0.26, 2.22±0.26, 0.74±0.074kBq) and (0.3±0.03, 026±0.03, 0.11±0.01kBq) for the volume and planar sealed source, respectively, on 27 June 2018. The efficiency curves for the two sealed sources were determined in the energy range 36-1332.5keV, which were measured at 5cm from the HPGe-detector to determine the radioactivity levels of unknown samples for the neutron activation method.