Introduction: Cardiovascular diseases (CVD) are the world's most common cause of death. The Framingham risk score (FRS) is the most commonly used method for CVD risk assessment. Low-risk individuals have 10% or less coronary heart diseases (CHD) risk at 10 years, 10-20% have intermediate risk and 20% or more have high risk. Aim of Work: To estimate the risk of developing cardiovascular diseases over next ten years among the administrative
staff at Zagazig University, Egypt. Material and Methods: A structured questionnaire was used to get data about socio demographic characteristics, anthropometric measurements was done, laboratory investigations to measure
fasting and post brandial blood sugar and lipid profile. The Framingham risk score (FRS) was calculated by using information on age, gender, smoking ,
diabetes mellitus (DM), systolic blood pressure , treatment for hypertension
, and total blood cholesterol and high-density lipoprotein levels for every
subject. Results: About 55% of the studied sample were males and 44.8%
were females, the overall prevalence of systolic hypertension was 45.7% ,
36.2% had a positive family history of CVD , 25% were physically active
( the majority of them were males),21.5% were diabetic, 63.7% had high
blood cholesterol,55.1% had central obesity,68.1% were overweight or
obese. FRS mean for males was higher as compared to females (14.3±7.1
and11.9±5.8 respectively). Participants with high CVR risk were mainly
inactive, smokers, with positive family history, diabetics, hypertensive,
with high blood cholesterol level, high density lipoprotein and with central
obesity .A statistically significant positive correlation was observed between
FRS and age, cholesterol, systolic blood pressure, blood glucose ,weight ,
waist circumference and body mass index(BMI)  
Conclusion: About 42%
of our studied subjects were at low anticipated 10-year CVD risk, 30% were 
at moderate risk, and 28% of them were at high risk .The most significant
risk factors were male gender ,smoking, physical inactivity , hypertension,
diabetes mellitus, obesity, abdominal obesity , high levels of total cholesterol
and low HDL-cholesterol level in addition to positive family history . CVD
is a preventable public health issue; most of its risk factors are modifiable.