Introduction: COVID-19 is a real threat to Egypt which needs effective
preparedness for crisis of infections that could happen. Use of personal
protective equipment is pivotal to limit the transmission of COVID-19 in
the healthcare settings. Aim of Work: To assess the feasibility of a training
intervention program to HCWs (doctors, nurses, pharmacists, technicians
and workers) which was used to evaluate their level of knowledge regarding
COVID-19 pandemic, to promote their degree of confidence in using PPE,
and to improve their knowledge during the current pandemic. Materials
and Methods: A quasi-experimental study was carried out at Tanta Chest
Hospital. Participants answered a self-administered validated questionnaire
which included questions regarding socio-demographic, knowledge about
COVID-19 and confidence of the usage of PPE as a protective measure. The
questionnaire was used before and after intervention health education program
and training sessions. Results: Means of knowledge scores of physicians
and nurses after intervention (11.19±2.18 and 10.06±2.26 respectively) were
statistically significantly higher than all other subgroups of HCWs. Only 13.9%
of physicians, 6.0% of pharmacists, 10.7% of nurses, 2.4% of technicians and
no workers had high confidence regarding PPE as a preventive tools, and a
significant increase in confidence level after intervention to be (62.9%, 53.4%,
61.2%, 44.7% and 55.3%) respectively. A linear regression analysis revealed
that there was a statistically significant relation between high confidence in
PPE after intervention with increased years of experience and total knowledge
score. Conclusion: Intervention training program significantly increased
knowledge and confidence level of targeted participants in PPE. Hence,  ongoing training for HCWs is fundamental for health care personnel especially
during pandemics.