Introduction: Gastroenterologists spend considerable time performing endosᴄopic
procedures that necessitate repetitive motions. The number of endoscopic proᴄedures
performed by gastroenterologists has increased significantly in the past 20 years.
Among physicians, endoscopists faces increased risk for work-related musculoskeletal
disorders (WMSDs) compared to other physiᴄians who are not performing this
procedure. Aim of work: To determine the prevalence of musculoskeletal disorders
(MSDs) symptoms among the endoscopists and their assistants who are working in
Menofia University, Teaching and General hospitals in Menoufia governorate - Egypt
and to determine their risk factors. Also, to study the effects of MSDs on their work
and daily activities. Materials and methods: A comparative cross-sectional study was
done using a predesigned questionnaire to assess the musculoskeletal disorders among
gastrointestinal endoscopists who were compared with other physicians not performing
interventional procedures.Results: The present study showed that musculoskeletal
complaints were more evident among endoscopists, e.g., neck, shoulder, wrist, and
non-dominant thumb pain showed a statistically significant difference when compared
to the control group (26.1%, 68.7%, 30.4%, 52.2%, 56.5%), respectively, compared to
(15%, 17%, 19%, 10%, and 0%) respectively (p < 0.001). Endosᴄopists reported that
their pain interferes with daily life activities and cause sleep disorders. Endosᴄopists
who reported pain at different body sites present significant association after adjustment
with age (OR=4.95; 95% CI: 2.12-11.56) working duration > 10 years (OR=5.82; 95%
CI: 2.37-14.28), number of operations >3 /day (OR=4.53;95% CI: 2.03-10.09), duration
of single operation > half an hour (OR=3.80; 95% CI: 1.60-9.04) and the single hand
intubation technique (OR=8.0;95% CI: 3.10-20.62). Conclusion: The performance  of endoscopy puts the physicians at risk of biomechanical injury. Education of the
endosᴄopists toward correct ergonomic practices, the spacing between procedures is
required to improve the endoscopists' quality of life.