Introduction: In today's modern industrial world all manufacturing entities strive for sustaining the ever changing turmoil of varying resources and demands, a need for correcting and efficient managing of resources and time emerges. Hence, lean manufacturing techniques that have surfaced as the motor tool in controlling and nourish improving the quality of the business. Aim of work: To clarify the impact of implementing lean manufacturing system on the work environment and employees' health in the garment manufacturing in order to eliminate the environmental problems, such as air pollutants and hazard wastes. On the other side, lean manufacturing technique aims to eliminate wastes to create a more efficient workplace. Materials and methods: It begins by stating the principles and techniques of lean manufacturing system, and the tools used to achieve them. To be more accurate, everything must be related to its environmental effect. This research was applied at the assembly line of Textile Company for apparel Industries focusing on sewing section of Men's T-shirt model. Results: This research shows a good impact of implementing lean manufacturing system on work environment by reducing and eliminating production and environmental wastes. Conclusion: The research findings show the implementation of lean system can affect directly business and indirectly the work environment and human health. According to this study, quality has been improved; productivity, efficiency, cost has been reduced and profit have been increased. Also, total dust and particulates have been eliminated.