Introduction: Preparatory school teachers represent an occupational group who are prone to work related musculoskeletal disorder but its prevalence among teachers in Egypt has not been reported. Aim of work: To determine the prevalence of upper limb,lower limb, neck and back musculoskeletal disorders, to determine the relationship between teachers characteristics and musculoskeletal disorders and to investigate the relationship between physical risk factors and musculoskeletal disorders amongpreparatory governmental school teachers in Cairo, Egypt in the previous12 months.
Materials and methods: Convenience sample of 200 preparatory school teachers were selected from governmental schools in Cairo, Egypt, their mean age value was (35.9± 3.34) years, they were asked to answer a modified Nordic  estionnaire which assisted musculoskeletal disorder due to their work in last 12 months. Results: The prevalence of work related musculoskeletal disorders among Egyptian preparatory school teachers were 96% in the previous 12 months. The prevalence was significantly higher among females compared to males. The neck and back (83.5%) were the
most commonly affected parts followed by upper limb. Standing for long periods of time and high workload were significantly related to upper limb, lower limb, neck and back injuries. About 18.9% of teachers took sick leave (from 1to 7 days) due to their injuries. Conclusion: the prevalence of work related musculoskeletal disorders among preparatory school teachers in Cairo, Egypt is high as in comparison to their counterparts around the world.