Introduction: inspiratory muscle training (IMT) improves exercise capacity and ventilatory responses to exercise in chronic heart failure (CHF) patients with inspiratory muscle weakness (IMW). Aim of work: To investigate the effect of inspiratory muscle training (IMT) with comprehensive cardiac rehabilitation (CR) program (aerobic and resisted exercise training) on cardiac parameters of exercise tolerance test in chronic heart failure patients Materials and Methods: Forty eligible male patients with chronic heart failure secondary to ischemic heart disease (only thirty of them completed the study). Their ages ranged from 50-60 years old .They were randomly assigned to 6 months of aerobic exercise , resisted exercise plus IMT (n=15) or to aerobic exercise plus resisted exercise only (n=15), before and after intervention, the following measures were obtained :cardiac parameter of cardiopulmonary exercise testing ( maximum heart rate , resting heart rate ). Result: Compared aerobic exercise (AE) + IMT to AE resulted in cardiac parameters of exercise tolerance test (maximum heart rate, resting heart rate) improved similarly in the 2 groups. Conclusion: This study demonstrated that the addition of IMT to AE results in improvement in cardiac response to exercise in selected patients with CHF but with no significant difference between exercise training groups.