ِِِِِِِِِِِِِِِِِِِِِِِِANTIBACTERIAL activity of acetone, ethanol and water extracts of parts of the indigenous in Syria wild myrtle Myrtus communis L., (root, stem, leaves, fruits) with different concentrations (25, 50, 75, 100%) was carried out against gram-positive bacteria growth which isolated and identified from the pathogenic specimens of Damascus Children's Hospital, Bacterial laboratory, using agar well diffusion method on Mueller – Hinton medium. The results showed the effect of Myrtle extracts concentration on bacterial growth, increasing concentration causes rise inhibition diameter of bacterial growth. The effect of Myrtle acetone extracts was more effective against Staphylococcus epidermidis and Staphylococcus aureus, and the best effect of parts extracts of both plants was better on the two types of bacteria as follows: leaves> fruits> stem> roots, increasing concentration succeeded to increase inhibition zone of bacterial growth, and results showed that acetone extracts induced pronounced effectiveness of the largest in the two types of bacteria, followed by ethanolic then aqueous extracts, inhibition effective against S. epidermidis was more much than S. aureus . Generally, the effect of blue myrtle parts extracts was more effective on bacteria than white type. This study also confirmed the antimicrobial potential of investigated plants and their usefulness in the treatment of resistance gram-positive microorganisms.