Lambs mortality was noticed in Sidi-Barrani City, Matrouh Governorate, Egypt during winter season, 2014 - 2015. One of them, a three-month-old female lamb died after signs of fever accompanied with some respiratory manifestations firstly and dullness, inability to move and weight loss for over seven days later, without response to tetracycline treatment. Necropsy revealed multifocal caseous abscesses in the lungs and liver. Klebsiella pneumoniae was isolated from these lesions. The bacterial isolate was resistant to Tetracyclin (in vitro), which is the most common used antimicrobial agent for animal treatment in this region. On the other hand, it was susceptible to Gentamycin and Chloramphenicol.