SOME morphological, physiological and biochemical responses of tomato plant cv. 010 were determined using amino acids (Amino-Suam) and micronutrient solution include (2% Fe, 2% Zn, 2% Mn, 1% Cu and 0.5% B) individually and in combination. Two field experiments were conducted on September, 2017/2018 and 2018/2019 at the Faculty of Agriculture, Ain Shams University Farm, Shoubra El-Kheima, Cairo, Egypt. Three levels of Amino-Suam (0, 1000 and 2000ppm), micronutrients solution (0, 500 and 1000ppm) and their combinations were designed in complete randomized block design with three replications for each treatment and sprayed at 30, 45 and 60 days after transplanting. Results revealed that spraying with amino acids, micronutrients solution and their combinations stimulated vegetative growth parameters and yield components including shoot height, number of branches and leaves per plant, leaf area, leaf fresh weight, number of fruits per plant, average fruit weight, fruit diameter and total fruit yield/fed compared to control plants in both seasons. Data suggested that combination treatments achieved significant increases of most vegetative growth parameters, and some biochemical constituents such as N, Fe, Mn, Cu, photosynthetic pigments and total soluble proteins in tomato leaves at 75 days after transplanting as well as fruits yield, lycopene and ascorbic acid concentrations in fruits at harvest compared to control plants in both seasons.