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Synthesis and Microstructure Characterization of Novel Sr-HA Prepared by Co-precipitation with Enhanced Bioactivity

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Last updated: 01 Jan 2025

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Abstract

  THERE IS accumulating evidence that strontium-containing biomaterials have positive effects on bone tissue repair. In this study, a series of Sr-substituted hydroxyapatites (SrxCa1-x)5 (PO4)3OH, where x = 0.00, 0.5, 1.00 and 2.00 were made by the co-precipitation method. The microstructure analyses of obtained apatite after incorporation of Sr were evaluated by using X-ray Diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Scanning electron microscope (SEM) and Thermo gravimetric analysis (TGA). Moreover, bioactivity of samples was examined by soaking samples in the simulated body fluid solution (SBF). Strontium is quantitatively incorporated into hydroxyapatite where its substitution for calcium provokes a linear increase in the lattice constants and a linear shift of the infrared absorption bands of the hydroxyl and phosphate groups, coherent with the greater ionic radius of strontium .Also incorporation of Sr into hydroxyapatite provokes its thermal stability and bioactivity. The obtained results indicate that Sr-HA have high potential to be used as a resorbable scaffold material release therapeutic agent to enhance osteogenesis and bone regeneration.

DOI

10.21608/ejbbe.2012.1194

Keywords

Hydroxyapatite, Sr-substituted hydroxyapatite, Crystal size, Bioactivity, Simulated body fluid

Volume

13

Article Issue

1

Related Issue

108

Issue Date

2012-12-01

Receive Date

2014-02-25

Publish Date

2012-12-31

Page Start

73

Page End

85

Print ISSN

1110-8525

Online ISSN

2357-0911

Article File

EJBBE_Volume 13_Issue 1_Pages 73-85.pdf

PDF . 501.5kB

Link

https://ejbbe.journals.ekb.eg/article_1194.html

Detail API

https://ejbbe.journals.ekb.eg/service?article_code=1194

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6

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Original Article

Type Code

109

Publication Type

Journal

Publication Title

Egyptian Journal of Biomedical Engineering and Biophysics

Publication Link

https://ejbbe.journals.ekb.eg/

MainTitle

Synthesis and Microstructure Characterization of Novel Sr-HA Prepared by Co-precipitation with Enhanced Bioactivity

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Article

Created At

22 Jan 2023