Water quality in freshwater bodies is involved by multiple aspects such as physical, chemical, and biological processes and their interactions. It is vital for aquatic species' survival and growth. This study investigated to assess water quality parameters and the correlation between the water quality parameters and catch per unit effort for oriental river prawn (Macrobrachium nipponense). During 2015 (from January to December), we sampled water and specimens of M.nipponense simultaneously from the Anzali lagoon. All physicochemical parameters were sampled and determined according to standard methods. The results showed the correlations (Fig. 2) between CPUE with physicochemical variables were significant and strong. The highest positive correlations were found between CPUE and temperature (R2 = 89, P < 0.05). The CCA results indicate the CPUE mainly was affected by water temperature and pH. The CCA results clearly separated all sites based on water quality.