Rissoides desmaresti shrimp is a good source of a high nutritional value, which makes it a very healthy food choice for humans. The relationship between the environmental factors (temperature, salinity, pH value, and dissolved oxygen) and the nutritive values of Rissoides desmaresti (Crustacean- Stomatopoda) was addressed and the factors were seasonally measured in the current study. Concurrently, the nutritive values (crude protein, lipid, carbohydrate, calorific value, moisture, and ash) in the muscle tissue of Rissoides desmaresti were seasonally analyzed. The statistical analysis showed that the values of the correlation coefficient for different biochemical composition parameters with the ecological factors ranged between very strong positive correlation and very strong negative correlation. The relationships were different; the most influential detected factor was salinity, followed by temperature, dissolved oxygen, and pH. Remarkably, these constituents are affected by the alteration in ecological factors, forming an indicative indicator to know how far the organism is affected by those factors, and detect their permanent change associated with the climatic changes.