The current study was conducted to address thirty nine immigrant fish species collected from the Red sea and recorded in previous studies in seven regions of the Egyptian Mediterranean waters during the period from 2013- 2021. A total number of 13212 fish specimens were determined in this study. They were divided according to their importance in the fish markets into economic (18) and non-economic species (21). Thirteen new fish species were identified in the present work whereas 15 fish species in the checklist given by Halim and Rizkalla (2011) were not found in the study area within the study period. The fish occurrence was determined in the different studied regions (Port- Said, Damietta, Abu Qir, Alexandria, El-Agami, El- Dabaa, and Marsa Matruh). On basis of occurrence, fish species were classified into rare, frequent and abundant. With an occurrence percentage of 49.1 including all fish species, Port- Said (North opening of Suez Canal) was recorded the highest among all studied regions, followed by Alexandria (41.9%), Abu-Qir (5.2%) and Marsa Matruh (3.7%). Considering species dominance in different regions; Alepes djedaba and Siganus rivulatus were the most dominant economic species found in Port Said, while Nemipterus randalli and Sargocentrum rubrum were abundant in Alexandria. In addition,   Nemipterus randalli was detected in Abu-Qir area whereas in Marsa Matruh, Upeneus pori was the most abundant. In conclusion, this study was established to determine the distribution of Lessepsian species along the seven studied regions of the Egyptian Mediterranean waters during the period from 2013 to 2021.