In fish, prior to ovulation, the process that includes oocyte maturation is essential for successful and guaranteed fertilization. In the current study, Cyprinus carpio L. oocytes were exposed to three different types of recombinant growth factors: Insulin-like growth factor (IGF), Fibroblast growth factor (FGF),  and Transforming growth factor (TGF). A sample of 5 ng /ml of the three upper- mentioned growth factors was utilized on common carp follicles for 3 different periods of time ( 24,48, and 72 hours). The current study was conducted from December 2019 till January 2020 at the college of veterinary medicine. The results recorded a significant effect (P<0.01) between the polarization index (PI) and the different times of incubation. Additionally, an interaction between the treatments and incubation time, using F test, was spotted. Using the Tukey test for multiple comparisons, a highly significant difference (P<0.01) between various treatments was noted, except for the comparable relationship between the control and G1.