This study deals with new modified chitosan beads with pendent amidoxime moieties [chitosan amidoxime chelating resin (CACR)] prepared by reaction of cross-linking chitosan beads with acrylonitrile and hydroxylamine. The resulting (CACR) resin was characterized using Fourier transform infrared, energy dispersive X-ray analysis, Scanning Electron Microscopy and BET surface area. To remove lead ions from aqueous solution the study was carried out under several variables include the initial concentration (50-250 mg/L), the amount of CACR (1-5 g/L), contact time (10-300 min) and the pH value (1.5-3.5) to indicate the removal efficiency of the (CACR). Glutaraldehyde. The batch experiment cited that the maximum adsorption efficiency of 55.5 mg/g was recorded at the optimum conditions of pH 3, 200 mg/L of Pb ions concentration and contact time 120min. using 2 g/L of [CACR]. The adsorption of lead ions with [CACR] follows the pseudo-second-order kinetics. The adsorption process was fitted to Langmuir and Freundlich isotherms models with slight advantage for the Langmuir approach.