Seasonal index is an important indicator to study seasonal variations in any studied phenomena which can be changed regularly in an interval less than one year. This paper aimed to study the relationship between fish catch & fish prices "Seasonal Index" of Egyptian Natural Fisheries. This relationship determines type of fisheries production, if this relationship is positive, then the fish catch from this fisheries are totally economic. Whereas the negative relationship means the fisheries need to apply new developing programs to be in economic production. The present work concluded that: (1) It is important to increase, or at least maintain fish catch in total Egyptian natural fisheries, total fresh water fisheries, total marine fisheries, and individual Red Sea fisheries due to the positive relationship between fish catch seasonal index (%) and fish prices seasonal index. (2) More and actual effective developing programs must be applied in total lakes fisheries and individual Mediterranean Sea fisheries to overcome the present negative relationship between seasonal index of fish catch and fish prices.