Amphibian diversity and abundance in relation to environmental change in Harenna Forest, BMNP was assessed using GIS and Remote sensing. Sampling of amphibian communities was conducted during July-August 2008 and February 2009; which includes wet and dry seasons in the area. Data on diversity, evenness and dominance was analyzed; seven endemic amphibian species belonging to one order, 5 families and 5 genera were recorded. The current results were compared with the past investigation of amphibians in the Harenna Forest. The results showed a decrease in abundance and diversity of amphibians over the past decades. GIS and Remote sensing methods using satellite images of the Harenna Forest were used to quantitatively analyze land use/land cover changes from 1973 to 2000. The results showed a significant reduction in the forest cover and wetlands followed by the establishment of new land use types, such as agricultural land and settlement in 2000.