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28517

Effect of Propofol Fresensius 1% on nervous system ultrastructure of Biomphalaria alexandrina.

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Last updated: 01 Jan 2025

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Abstract

This study was aimed to evaluate the effect of propofol fresensius 1% on the nervous system of Biomphalaria alexandrina snails, which represent the intermediate host of schistosoma mansoni after acute exposure (5ml/L) for 24 hours and chronic exposure (1ml/L) for 72 h, using scanning and transmission electron microscope. After chronic exposure, visceral ganglion was observed compressed and elongated, not paired with pedal ganglia and its nerves did not contact with it. 1ml/L propofol completely blocked synaptogenesis between visceral and pedal neurons. After acute exposure, the varicosities have few granular vesicles, whereas in the chronic exposure, the varicosities were empty and no granular vesicles were found inside it. Poorly developed endoplasmic reticulum, few Golgi bodies, elongated mitochondria, and more intercellular connective space were observed. 

DOI

10.21608/ejabf.2019.28517

Keywords

Propofol fresensius Nervous system, Biomphalaria alexandrina, Bioindicator, Golgi bodies

Authors

First Name

Hanan

Last Name

S. Mossalem

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Orcid

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First Name

Shereen

Last Name

M. Mansour

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Volume

23

Article Issue

1

Related Issue

4675

Issue Date

2019-01-01

Receive Date

2019-01-16

Publish Date

2019-03-09

Page Start

265

Page End

274

Print ISSN

1110-6131

Online ISSN

2536-9814

Article File

EJABF_Volume 23_Issue 1_Pages 265-274.pdf

PDF . 855.9kB

Link

https://ejabf.journals.ekb.eg/article_28517.html

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https://ejabf.journals.ekb.eg/service?article_code=28517

Order

22

Type

Original Article

Type Code

103

Publication Type

Journal

Publication Title

Egyptian Journal of Aquatic Biology and Fisheries

Publication Link

https://ejabf.journals.ekb.eg/

MainTitle

Effect of Propofol Fresensius 1% on nervous system ultrastructure of Biomphalaria alexandrina.

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Article

Created At

22 Jan 2023