The population structures and stock status of the goatfish (Family; Mullidae) were investigated from Hurghada, Red Sea, Egypt since these kinds of fish are important in different fields, such as fisheries, tourism…,etc. The fish samples were monthly collected from Hurghada harbor during the year 2016. The data available in the harbor and in the lab were taken for all species and the analysis was conductedfor the common three only. As a result, the goatfish was mainly caught by gillnet and trammelnets in the study area, and they were classified into seven species; Mulloidichthys  flavolineatus (Lacepède, 1801); M. vanicolensis (Valenciennes, 1831); Parupeneus forsskali (Four-manoir & Guézé, 1976); P. macronema (Lacepède, 1801); P. cyclostomus (Lacepède, 1801); P.rubescens (Lacepède, 1801); P. heptacanthus (Lacepède, 1801). The catch compositionof the Goatfish speciesby number showed that M.  flavolineatus was the most abundant species, constituted of 43%, followed by P. forsskali, and M. vanicolensis, constitutedof 19 %, and 12% respectively. Themaximum length and weight, and minimum length and weight of species and their seasonal occurrence, confirmed that the most common and dominant species were M.  flavolineatus, P.  forsskali; M. vanicolensis.The length frequency of M. flavoli-neatus ranged between11and 33.9cm TL, and the most dominant length group were at 19-19.9 cm TL. The length of M. vanicolensis ranged between 15 and 31 cm TL, and the most occurred lengths were at 27 cm TL. On the other hand, the length frequencies of P. forsskali varied between 11 and 27.9 cm, and the highest frequencies were at 18-18.9 cm TL. Sex ratio was 1:0.86, 1:0.47 and 1:1.01 for M.  flavolineatus, M. vanicolensis and P. forsskali, respectively. The mean total mortality coefficient "Z," estimated by two different methods, were found to be 1.49, 1.43 and 1.09year-¹ forM.  flavolineatus, M.vanicolensis, and P. forsskali respectively. The natural mortality coefficient "M" was estimated to be 0.48, 0.64 and 0.55year-¹ for M.  flavolineatus, M. vanicolensis, and P. forsskali, respectively. Exploitation rate "E" was computed as 0.68, 056 and 0.49 respectively. The relative yield of M. flavolineatusshould bereduced from 0.68 to 0.33 (45%), from 0.56 to 35 (39 %) for M. vanicolensis, andfrom 0.49 to 0.33 (32%) for P.  forsskali to maintain a sufficient spawning biomass.