The prime goals of the present study are to assess trends in the concentrations of the groundwater quality and evaluate this water for domestic, agriculture and various industrial processes.  Groundwater quality indicators were monitored, for the first time, for4 years (2011, 2013, 2014 and -2015) from three wells constructed in El-Sheikh Fadl, Bani Mazar, El Minya Governorate, Egypt. Quality indicators included pH, alkalinity, TDS, hardness, Na⁺,  k⁺, Mg²⁺, Ca²⁺, Cl^-, SO₄^2-, NO₃^-, S^2-, Al³⁺, Cu²⁺, Fe²⁺, Mn²⁺and Ni²⁺concentrations.Based on the outcomes, groundwater was classified as brackish water. Elevated pH, alkalinity, Ca²⁺, SO₄^2-, NO₃^-, S^2-, Al³⁺, Cu²⁺, Fe²⁺, Mn²⁺and Ni²⁺ concentrations were observed over monitoring years. Three main Varimax-rotated factors counted for 82.53 % of the total variance of the quality variables revealing how process like water-rock interaction, salinization and industrial pollution influence groundwater quality. The groundwater samples have a mixed mineralization that is possibly pure marine water affected by leaching and dissolution and cation exchange of both meteoric water (rainy water containing cement dust) and terrestrial salts. Groundwater is generally supersaturated with respect to calcite, dolomite and aragonite minerals. The water wells are not suitable for drinking and irrigation. For industrial, the groundwater needs further treatment.