The status of fishery in lake Manzala was evaluated during the period 1989-1998. Analysis of the annual catch variations of the total fish production and fishing effort indicated an increment in the index number of the total yield, effort and catch per unit effort by about 38.8 %, 5 % and 32% respectively during 1998. The annual variation in the total tilapia catch produced 57 % variation in the total fish yield during the period of this study. The estimated maximum sustainable yield for the total fish yield was about 64500 ton/year, while that of effort was 5405 boats and 16243 fishermen. The results indicated that the proper management of fisheries in lake Manzala can be achieved by reducing the current effort by 594 boats and 1842 fishermen. Analysis of the catch composition indicated that during 1998, the total fish yield consisted of miscellaneous group that including small fish of tilapia, mullets and others and this caused recruitment
overfishing of the fish stock in this lake.The present results showed that more than 90 % of the total yield was obtained from Mataria landing site and tilapia catch represents 49 % of it. The effect of the ecological factors
on fish and species composition was studied and the results were discussed.For the proper management of fishery in lake Manzala, some recommendation were given.