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2214

The protective role of copper nicotinate and vitamin E against neem seed oil induced oxidative stress and histopathological changes in Nile Tilapia (Oreochromis niloticus, Linnaeu

Article

Last updated: 01 Jan 2025

Subjects

-

Tags

Fisheries

Abstract

The aim of the current investigation was to evaluate whether neem (Azadirachta indica) seeds oil (NO) induced changes on some oxidative indicators and histopathological alterations in tissues of Oreochromis niloticus fish and the possible
protective effects of copper nicotinate (CN) and vitamin E on neem oil-induced changes. Fish were divided into 8 groups and treated with NO alone or in combination with CN, vitamin E and clean water. NO interfered with the antioxidant defense system of O. niloticus, as there was a decrease in GST, CAT and SOD activities in all studied organs as compared to control group. These alterations in antioxidantsactivities were accompanied with the occurrence of histological lesions and damage in  gills, liver and posterior kidney tissues. The addition of CN and Vitamin E in fish
diets could protect the fish O. nilotcus against NO-induced oxidative damage and histopathological changes showing recovery of fish organs. It was concluded that although botanical pesticides are being considered as less toxic/safe, but it may provoke deleterious changes in vital organs of the fish. Hence, precautions must be taken into account when botanicals are being used in fish production facilities. 

DOI

10.21608/ejabf.2014.2214

Keywords

Oreochromis niloticus, neem seed oil, Oxidative Stress, histopathology changes, copper nicotinate, Vitamin E

Authors

First Name

Ashraf

Last Name

El-Badawi

MiddleName

-

Affiliation

Central Laboratory for Aquaculture Research, Abbassa, Abo-Hammad, Sharkia, Egypt. 2- Biological Department,University College,Umm Al-Qura University,Kingdom of Saudi Arabia.

Email

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City

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Orcid

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First Name

Alkhateib

Last Name

Gaafar

MiddleName

-

Affiliation

Hydrobiology Department, National Research Centre, Dokki 12622, Giza, Egypt.

Email

-

City

-

Orcid

-

First Name

Hossam

Last Name

Abbas

MiddleName

-

Affiliation

Hydrobiology Department, National Research Centre, Dokki 12622, Giza, Egypt.

Email

-

City

-

Orcid

-

First Name

Mohammad

Last Name

Authman

MiddleName

-

Affiliation

Hydrobiology Department, National Research Centre, Dokki 12622, Giza, Egypt.

Email

-

City

-

Orcid

-

Volume

18

Article Issue

3

Related Issue

449

Issue Date

2014-09-01

Receive Date

2017-04-04

Publish Date

2014-09-01

Page Start

1

Page End

19

Print ISSN

1110-6131

Online ISSN

2536-9814

Link

https://ejabf.journals.ekb.eg/article_2214.html

Detail API

https://ejabf.journals.ekb.eg/service?article_code=2214

Order

1

Type

Original Article

Type Code

103

Publication Type

Journal

Publication Title

Egyptian Journal of Aquatic Biology and Fisheries

Publication Link

https://ejabf.journals.ekb.eg/

MainTitle

The protective role of copper nicotinate and vitamin E against neem seed oil induced oxidative stress and histopathological changes in Nile Tilapia (Oreochromis niloticus, Linnaeus, 1758)

Details

Type

Article

Created At

22 Jan 2023