This study was conducted to determine the suitability of dried Goat Manure Meal (GMM) as an ingredient for tilapia (Oreochromis spilurus) feed. Five experimental diets (I, 11, 111, IV and V) were formulated to contain 35%, 30%,25%,20% and 15% crude protein respectively. Diet I without GMM and contained fish meal, minerals, vitamins, lipids, dextrin, a-ce!lulose and carboxymethylcellulose (binder). Diets 11,111,IV and V contained GMM as a substitution to part of the fish meal. Diet VI contained 100% GMM and it had 19.4% crude protein. The 56-day feeding trial was conducted in triplicates treatment in 200 L circular fiber glass tanks with sea water which was changed every 4 hours. The maximum growth rate was obtained with diet I (control). There was a trend of reduced growth performance and FCR with increase in GMM level for all treatments. Significant decreases (P70.05) of lipid levels and increases of carbohydrates and ash levels of the fish muscles were recorded. However, the maximum saving of fish meal with good weight gain and FCR were obtained with the diet containing 19.8 GMM. Because of the low price of tilapia, it is not economical to feed them with high protein, expensive feed. Therefore, it can be concluded that low inclusion of GMM in tilapias diet is recommended.