This investigation was carried out during 2004, 2005, 2006 and 2007 seasons on Manfalouty pomegranate cultivar (Punica granatum L.) to study the effect of removing the suckers and girdling on yield components and fruit quality of Manfalouty pomegranate.  The experimental trees were divided into two treatments (non-suckering and suckering), while subtreatments were girdling (G) at a level of 0 (control), 3, 6, 9 mm thickness. The results showed that suckering combined with girdling 3, 6, 9 mm significantly increased the carbohydrate/nitrogen (C/N ratio), fruit set percentage, yield, commercial yield percentage and improved the total soluble solids percentage and reducing sugars.  Suckering and girdling 3 mm was the best practice compared with non-suckering.  While, suckering monthly and girdling 9 mm decreased the yield and fruit quality during the third and fourth year.  Moreover, non-suckering with girdling decreased gradually the yield and fruit quality during experimental seasons.                 It can be recommend that suckering combined with girdling have the best effect on C/N ratio, yield and fruit quality of Manfalouty pomegranate.  Also, girdling main trunks tree with 3 mm zone was suitable treatment during four studied experimental seasons.