This study was conducted to evaluate the impact of bio-fertilization with amino acids (500 and 1000 ppm), active dry yeast (5.0 and 10.0 g/L), and plant extracts as turmeric (500 and 1000 ppm) and cinnamon (500 and 1000 ppm) on yield and fruit quality of Sewi date palm during 2019 and 2020 seasons. All treatments were foliar sprayed twice, one month after pollination at Hababouk stage and two months later in Khalal Stage. The experiment was arranged in a randomized complete block design (RCBD) including nine treatments with ten replications of one bunch each. Data showed that all treatments had a positive effect on improving all studied characteristics under the investigation. Among treatments, foliar application of active dry yeast at 5.0 or 10.0 g/L significantly induced the best results for improving the yield and fruit attributes in terms of bunch weight (kg/palm), fruit retention percentage, fruit weight, fruit volume, pulp percentage, fruit length, fruit diameter, fruit shape index, total sugar percentage, reducing sugar percentage, and non-reducing sugar percentage during the two seasons of the study. Turmeric extract also was shown to be the best second treatment followed by amino acids then cinnamon extract. Hence, it could be concluded that spraying with amino acids, yeast, turmeric extract, and cinnamon extract can be used effectively on enhancing yield and fruit value of Sewi date palm.