A filed experiment was carried out at Al-Mattana Agricultural Research station, Agricultural Research Center, Luxor Governorate during 2015/16 and 2016/17 seasons, to study the effect of intercropping soybean (cover crop) with sugarcane crop, sole sugarcane and weed control treatments i.e. (Stomp at 1.75 l/f. hand hoeing twice at 25 and 45 days after planting and unweeded check) as the integrated weed control on fresh and dry weight of weeds (g/m²) and yield of primary crop (sugarcane) and secondary crop (soybean) which intercropping with sugarcane in natural infested soil by weeds. The experiment was laid out in randomized complete block design (RCBD) under split plot arrogant with four replication, intercropping treatments was put in the main plots and weed control treatment in split plots with four replications for each treatment.