Tomatoes are affected by insect pests which reduce their quantity, quality and profitability. The tomato leaf miner, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) can cause 100% yield loss. Field trials were conducted to evaluated six insecticides and four of their mixtures against this pest under field conditions. The six evaluated insecticidal treatments were applied in two consequent sprays within an interval of 17 days between each, in addition to the treatment of untreated check. The lonely or individually evaluated insecticides included indoxacarb, emamectin benzoate, spinosad, imidacloprid, lambda-cyhalothrin and acetamiprid which sprayed according to the recommendations of the Egyptian Ministry of Agriculture. Meanwhile, their evaluated mixtures emamectin benzoate+ lambda-cyhalothrin, indoxacarb + abamectin, emamectin benzoate + methomyl and abamectin + thiamethoxam were applied at the rate of half recommended dose of each insecticide within the tested mixture. All the insecticides alone or in combination were significantly better than untreated check in reducing pest population. The average reduction percentages for insecticides alone against leaf miner after first spray were 68.9, 64.9, 56.2, 50.5, 47.3 and