This study was conducted to evaluate the effect of spraying some growth regulators (CPPU at 15 ppm and GA₃ at 100 ppm), some antioxidants (Amino acids at 0.50 g/L, citric acid at 500 ppm and ascorbic acid at 500 ppm) and active dry yeast at 10 g/L on yield and fruit quality of Seewy date palm during 2015 and 2016 seasons. The experiment was set up in a complete randomized block design with seven treatments and ten replicates, one bunch per each. Date palm were sprayed three times, at the 1^st week of May, June and July. Foliar application had a positive effect on yield and fruit quality of Seewy date palm. The best results were obtained with spraying GA₃ at 100 ppm and CPPU at 15 ppm for increasing bunch weight, yield/palm, fruit weight, fruit length and diameter. On the other hand, spraying amino acids at 0.50 g/L and yeast at 10 g/L significantly increased TSS%, total sugars contents, and significantly decreased tannins %, total acidity % and fruit moisture content. So, it can be concluded that spraying GA₃ or CPPU combined with any amino acid, yeast, citric acid or ascorbic acid three time (1, 2 & 3 month of pollination time) increased the palm yield and improved the fruit quality of Seewy date palm.