The present investigation was carried out during 2013, 2014 and 2015 seasons to study the effect of plant extracts on growth and fruiting of Flame Seedless grapevines. The experiment was arranged in a randomized complete block design in which the study involved seven treatments with three replications, two vines each. Pruning wood weight, leaf area and leaf chlorophyll were significantly increased by spraying either garlic, turmeric or roselle extracts compared to unsprayed ones. Spraying garlic, turmeric or roselle extracts were very effective in improvement the yield/vine and cluster traits. Moreover, these treatments significantly improved the berry quality in terms of increasing the berry weight, total soluble solids and anthocyanin in skin of berries compared to unsprayed ones. The best results were obtained on the vines that sprayed with 0.2% turmeric extract. No significant differences were obtained among the tested extract. It could be concluded that spraying turmeric, roselle or garlic extract at 0.1% three times annually was necessary to get high yield with good cluster and berry quality of Flame Seedless grapevines.